Studies on Microbial Biosynthesis of Pantothenic Acid

Pantothenic Acid – Applications, Synthesis and Biosynthesis

PANTOTHENIC ACID – APPLICATIONS, SYNTHESIS AND BIOSYNTHESIS (Abstract): Pantothenic acid, also known as vitamin B5 or anti-stress vitamin, is a water-soluble vitamin with various applications in pharmaceutical industry (ointments, solut ions for treating lesions and irritation of the skin or mucous membranes, multivitamin supplements tablets, capsules, effervescent tablets, chewable tablets, sy...

Microbic Decomposition of Pantothenic Acid.

The metabolism of pantothenic acid.

The formulation of this pathway was based on: (a) the finding that cysteine supplies the sulfur-containing moiety of CoA (3,4); (b) the activities of pantetheine and pantothenylcysteine as growth factors for Acetobacter suboxydans (4-6) and Lactobacillus helveticus (7); (c) the presence of enzymes in these two organisms and also in Lactobacillus bulgur&s which decarboxylate pantothenylcysteine ...

The Effects of Pantothenic Acid on Respiratory Activity

Experiments using the Warburg-Barcroft apparatus led to the following results and conclusions: (1) Two yeasts in three different media were strikingly stimulated in their respiration by minute amounts of pantothenic acid. (2) Nine other compounds (vitamins and other biologically important substances) were tested and found in all cases to have on the deficient G.M. yeast, lesser and in some case...

Antagonism of L(-)pantothenic acid on lipid metabolism in animals.

The inhibition rate of L(-)pantothenate as an antagonist of D(+)pantothenate was discussed from the viewpoint of growth and lipid metabolism. The growth rate of mice given pantothenate-deficient diets containing L(-)pantothenate (300 mg per 100g diet) was markedly decreased, and such pantothenate-deficient symptoms as "spectacle eyes" appeared. However, it was recovered by the simultaneous addi...